Hypersensitivity to barbiturates or any part from the formulation; ; historical past of manifest or latent porphyria

These agents ought to only be blended if alternate treatment options are insufficient. If put together, Restrict the dosages and duration of each and every drug. Consider therapy modification

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butabarbital will reduce the level or outcome of pitolisant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Pitolisant publicity is reduced by 50% if coadministered with robust CYP3A4 inducers.

Primidone: May improve the adverse/poisonous result of Barbiturates. Primidone is converted to phenobarbital, and so results in being additive with existing barbiturate therapy. Monitor therapy

This medication can be useful for other purposes; request your well being care supplier or pharmacist Should you have questions.

This medication may well cause you to do issues while you're continue to asleep that you might not try to remember another early morning. It is achievable you could potentially push a car or truck, sleepwalk, have sex, make cellphone calls, or prepare and take in food stuff if you are asleep or not thoroughly awake. Notify your health care provider right away for those who master that any of those has happened.

Employing alcohol or tobacco with certain medicines may additionally bring about interactions to come about. The subsequent interactions have been picked on The premise of their prospective significance and are not necessarily all-inclusive.

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butabarbital will decrease the extent or outcome of dexamethasone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

butabarbital will minimize the extent or impact of solifenacin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.

butabarbital will lessen the extent or effect of ketoconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Not known.

butabarbital will minimize the level or impact of methylprednisolone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

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